Article
Incomplete T cell receptor V beta allelic exclusion and dual V beta-expressing cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 1995
Balomenos D, Balderas R S, Mulvany K P, Kaye J, Kono D H, Theofilopoulos A N
Abstract excerpt
Recent studies have documented incomplete TCR V alpha-chain allelic exclusion and dual V alpha-bearing T cells. Herein, we show that V beta allelic exclusion is also incomplete, since a significant proportion of peripheral T cells express dual V beta in both TCR transgenic and normal mice. Studie...
Topics
- Alleles
- Animals
- Base Sequence
- Immunoglobulin Variable Region
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic
- Molecular Sequence Data
- RNA
- Receptors, Antigen, T-Cell, alpha-beta
- T-Lymphocytes