Article
Crosses of NOD mice with the related NON strain. A polygenic model for IDDM.
Diabetes - 1 Oct 1995
McAleer M A, Reifsnyder P, Palmer S M, Prochazka M, Love J M, Copeman J B, Powell E E, Rodrigues N R, Prins J B, Serreze D V
Abstract excerpt
Chromosome locations of non-major histocompatibility complex (MHC) genes contributing to insulin-dependent diabetes mellitus (IDDM) in mice have been determined by outcrossing NOD mice to other inbred strains congenic for the NOD MHC haplotype (H2g7). At least nine non-MHC IDDM susceptibility genes (Idd) were previously identified at first backcross (BC1) after outcross of NOD to C57BL/10.H2g7 congenic mice...
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