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Conditioning the genome identifies additional diabetes resistance loci in Type I diabetes resistant NOR/Lt mice.

Genes and immunity - 1 Sept 2005

Reifsnyder P C, Li R, Silveira P A, Churchill G, Serreze D V, Leiter E H

Abstract excerpt

While sharing the H2g7 MHC and many other important Type I diabetes susceptibility (Idd) genes with NOD mice, the NOR strain remains disease free due to resistance alleles within the approximately 12% portion of their genome that is of C57BLKS/J origin. Previous F2 segregation analyses indicated multiple genes within the 'Idd13' locus on Chromosome 2 provide the primary component of NOR diabetes resistance....

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Identifiers

PMID: 16015371
DOI: 10.1038/sj.gene.6364241

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F2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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