Lack of effect of retinoic acid and fluocinolone acetonide on mirex tumor promotion indicates a novel mirex mechanism.

doi:10.1093/carcin/16.9.2199

Back to search

Article

Lack of effect of retinoic acid and fluocinolone acetonide on mirex tumor promotion indicates a novel mirex mechanism.

Carcinogenesis - 1 Sept 1995

Kim T W, Smart R C

Abstract excerpt

Mirex, a halogenated hydrocarbon, is a potent skin tumor promoter in 7,12-dimethylbenz[a]anthracene (DMBA)-initiated mouse skin. In the present study retinoic acid (RA) and fluocinolone acetonide (FA), classical inhibitors of phorbol ester- and non-phorbol ester-type skin tumor promoters, were ex...

Topics

9,10-Dimethyl-1,2-benzanthracene
Animals
Anticarcinogenic Agents
Base Sequence
Carcinogens
Cell Division
Drug Interactions
Ear, External
Edema
Female
Fluocinolone Acetonide
Genes, ras
Genotype
Mice
Mice, Inbred Strains
Mirex
Molecular Sequence Data
Papilloma

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.