Synergistic interaction between the non-phorbol ester-type promoter mirex and 12-O-tetradecanoylphorbol-13-acetate in mouse skin tumor promotion.

doi:10.1093/carcin/15.1.47

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Article

Synergistic interaction between the non-phorbol ester-type promoter mirex and 12-O-tetradecanoylphorbol-13-acetate in mouse skin tumor promotion.

Carcinogenesis - 1 Jan 1994

Meyer S A, Kim T W, Moser G J, Monteiro-Riviere N A, Smart R C

Abstract excerpt

Mirex, an organochlorine pesticide and non-genotoxic rodent hepatocarcinogen, is also a potent non-phorbol ester-type promoter of mouse skin tumors. Mirex, unlike most other skin tumor promoters, is not a significant epidermal hyperplasiogen even at a maximally promoting dose (200 nmol). Experime...

Topics

Adenine
Animals
Base Sequence
Carcinogens
Dose-Response Relationship, Drug
Drug Synergism
Female
Genes, ras
Mice
Mice, Inbred Strains
Mirex
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Papilloma

Skin

Skin Neoplasms

Tetradecanoylphorbol Acetate

Thymidine

Source

Open in PubMed

Identifiers

PMID: 8293547
DOI: 10.1093/carcin/15.1.47

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8293547-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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