Article
Oncogenic Signaling Pathways Activated in DMBA-Induced Mouse Mammary Tumors
1 Oct 2005
Abstract excerpt
Only about 5% of human breast cancers can be attributed to inheritance of breast cancer susceptibility genes, while the balance are considered to be sporadic in origin. Breast cancer incidence varies with diet and other environmental influences, including carcinogen exposure. However, the effects of environmental carcinogens on cell growth control pathways are poorly understood. Here we have examined oncogenic...
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