Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutated K-ras gene analysis in a randomized trial of preoperative chemotherapy plus surgery versus surgery in stage IIIA non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 1995

Rosell R, Molina F, Moreno I, Martínez E, Pifarré A, Font A, Li S, Skacel Z, Gómez-Codina J, Camps C

Abstract excerpt

The observation that the proteins encoded by ras genes play a central role in the signalling pathways used by cells to respond to growth factors and the fact that mutated ras proteins are constantly promoting cell division have led to a PCR-based hunt for additional clinical information. In the present study, K-ras analysis draws the following conclusions: (1) K-ras point mutation frequency was higher in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genes, ras

Share to Genotype

Share to Lung Neoplasms

Share to Point Mutation

Share to Treatment Outcome

Source

Identifiers

PMID: 7551935
DOI: 10.1016/0169-5002(95)00421-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutated K-ras gene analysis in a randomized trial of preoperative chemotherapy plus surgery versus surgery in stage IIIA non-small cell lung cancer.PMID 7551935Read ↗

Across the universe of K-RAS mutations in non-small-cell-lung cancer.Semantic proximity Read ↗

Is there a prognostic role of K-ras point mutations in the serum of patients with advanced non-small cell lung cancer?Semantic proximity Read ↗

K-<i>ras</i>Oncogene Activation as a Prognostic Marker in Adenocarcinoma of the LungSemantic proximity Read ↗

Molecular staging of non-small cell lung cancer according to K-ras genotypes.Semantic proximity Read ↗

K-ras genotypes and prognosis in non-small-cell lung cancer.Semantic proximity Read ↗

Correlation between K-ras gene mutation and prognosis of patients with nonsmall cell lung carcinoma.Semantic proximity Read ↗

Implications and prognostic value of K-ras mutation for early-stage lung cancer in women.Semantic proximity Read ↗

Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer.Semantic proximity Read ↗

K-ras oncogene mutation as a prognostic marker in non-small cell lung cancer: a combined analysis of 881 cases.Semantic proximity Read ↗

Lack of prognostic significance of p53 and K-ras mutations in primary resected non-small-cell lung cancer on E4592: a Laboratory Ancillary Study on an Eastern Cooperative Oncology Group Prospective Randomized Trial of Postoperative Adjuvant Therapy.Semantic proximity Read ↗

Detection of K-ras mutations in lung carcinomas: relationship to prognosis.Semantic proximity Read ↗

Automated real-time PCR to determine K-ras codon 12 mutations in non-small cell lung cancer: comparison with immunohistochemistry and clinico-pathological features.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.