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Article

Mutated K-ras gene analysis in a randomized trial of preoperative chemotherapy plus surgery versus surgery in stage IIIA non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 1995

Rosell R, Molina F, Moreno I, Martínez E, Pifarré A, Font A, Li S, Skacel Z, Gómez-Codina J, Camps C

Abstract excerpt

The observation that the proteins encoded by ras genes play a central role in the signalling pathways used by cells to respond to growth factors and the fact that mutated ras proteins are constantly promoting cell division have led to a PCR-based hunt for additional clinical information. In the p...

Topics

Antineoplastic Combined Chemotherapy Protocols
Carcinoma, Non-Small-Cell Lung
Cisplatin
Combined Modality Therapy
DNA Mutational Analysis
DNA, Neoplasm
Genes, ras
Genotype
Humans
Ifosfamide
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitomycin

Point Mutation

Remission Induction

Survival Rate

Treatment Outcome

Source

Identifiers

PMID: 7551935
DOI: 10.1016/0169-5002(95)00421-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7551935-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mutated K-ras gene analysis in a randomized trial of preoperative chemotherapy plus surgery versus surgery in stage IIIA non-small cell lung cancer.PMID 7551935Read ↗

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