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Article

Automated real-time PCR to determine K-ras codon 12 mutations in non-small cell lung cancer: comparison with immunohistochemistry and clinico-pathological features.

International journal of oncology - 1 Oct 2003

Hilbe Wolfgang, Dlaska Margit, Duba Hans-Christoph, Dirnhofer Stephan, Eisterer Wolfgang, Oberwasserlechner Frieda, Mildner Andreas, Schmid Thomas, Kühr Thomas, Wöll Ewald

Abstract excerpt

A real-time PCR technique with automated computerized analysis (TaqMan ) was tested to detect K-ras mutations in 66 patients suffering from NSCLC. This technology is characterized by high reproducibility of data and a time-saving analysis procedure. In 11% (7/66) of the tumour specimens and 2% (1/58) of adjacent tumour-free lung specimens a K-ras codon 12 mutation was detected. In adenocarcinomas containing > or...

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PMID: 12963994

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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