Article
Molecular staging of non-small cell lung cancer according to K-ras genotypes.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 1996
Rosell R, Monzó M, Pifarré A, Ariza A, Sánchez J J, Moreno I, Maurel J, López M P, Abad A, de Anta J M
Abstract excerpt
We have previously demonstrated a strong association between K-ras gene mutations, as determined by PCR followed by allele-specific oligonucleotide hybridization (ASO-h), and survival in non-small cell lung cancer patients. The purpose of this study was to determine the relationship between tumor aggressiveness and specific-type K-ras point mutations in non-small cell lung cancer. We developed procedures to...
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