Article
Analysis of mouse hemoglobin alpha-chain locus mutation induced by N-ethyl-N-nitrosourea.
Idengaku zasshi - 1 Aug 1995
Murota T
Abstract excerpt
In a mouse specific-locus test in stem-cell spermatogonia of mice after treatment with N-ethyl-N-nitrosourea (ENU), a mutation at the hemoglobin alpha-chain locus was obtained. In an original mutant, the mutation was detected as a change in band density using cellulose acetate electrophoresis, e....
Topics
- Animals
- Crosses, Genetic
- Ethylnitrosourea
- Genotype
- Hemoglobins
- Homozygote
- Isoelectric Focusing
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred Strains
- Mutagenesis
- Mutagens
- Protein Structure, Secondary
- Spermatogonia