Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2011

Aigner Bernhard, Rathkolb Birgit, Klempt Martina, Wagner Sibylle, Michel Dian, Klaften Matthias, Laufs Jürgen, Schneider Boris, Sedlmeier Reinhard, Hrabé de Angelis Martin, Wolf Eckhard

Abstract excerpt

Research on hematological disorders relies on suitable animal models. We retrospectively evaluated the use of the hematological parameters hematocrit (HCT), hemoglobin (HGB), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), red blood cell count (RBC), white blood cell count (WBC), and platelet count (PLT) in the phenotype-driven Munich...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ethylnitrosourea
Share to Hematologic Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematologic Tests

Share to Mice, Inbred C3H

Share to Mutagenesis

Share to Mutagens

Share to Receptors, Transferrin

Share to Reference Values

Source

Identifiers

PMID: 21553221
DOI: 10.1007/s00335-011-9328-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.PMID 21553221Read ↗

Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels.Semantic proximity Read ↗

ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level.Semantic proximity Read ↗

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels.Semantic proximity Read ↗

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.Semantic proximity Read ↗

[Optimization ofPig-aGene Mutation in Rats and Assessment of Time-dependent and Dose-response Relationship of N-ethyl-N-nitrosourea].Semantic proximity Read ↗

Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency.Semantic proximity Read ↗

A Mouse Model for Human Unstable Hemoglobin Santa Ana.Semantic proximity Read ↗

Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models.Semantic proximity Read ↗

N-ethyl-N-nitrosourea-based generation of mouse models for mutant G protein-coupled receptors.Semantic proximity Read ↗

Generation of ENU-induced mouse mutants with hypocholesterolemia: novel tools for dissecting plasma lipoprotein homeostasis.Semantic proximity Read ↗

A novel ENU-induced Cpox mutation causes microcytic hypochromic anemia in mice.Semantic proximity Read ↗

Large-scale N-ethyl-N-nitrosourea mutagenesis of mice--from phenotypes to genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.