Studies on mutations in male germ cells of transgenic mice following exposure to isopropyl methanesulfonate, ethylnitrosourea or X-ray.

doi:10.1016/0165-1218(94)90020-5

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Article

Studies on mutations in male germ cells of transgenic mice following exposure to isopropyl methanesulfonate, ethylnitrosourea or X-ray.

Mutation research - 1 Nov 1994

Katoh M, Inomata T, Horiya N, Suzuki F, Shida T, Ishioka K, Shibuya T

Abstract excerpt

Transgenic mice have recently been used for mutagenesis assays in vivo. The present study was undertaken to clarify whether such assays can detect mutations induced after treatment of male germ cells in mouse with isopropyl methanesulfonate (iPMS), ethylnitrosourea (ENU) or X-ray irradiation. The...

Topics

Animals
Ethylnitrosourea
Germ Cells
Lac Operon
Male
Mesylates
Mice
Mice, Transgenic
Mutation
Spermatozoa
Testis

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