Genetic analysis of an N-ethyl-N-nitrosourea-induced mutation at the hemoglobin beta-chain locus in mice.

doi:10.1016/0165-7992(82)90162-2

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Article

Genetic analysis of an N-ethyl-N-nitrosourea-induced mutation at the hemoglobin beta-chain locus in mice.

Mutation research - 1 Jan 2000

Murota T, Shibuya T, Tutikawa K

Abstract excerpt

The specific-locus test was performed with N-ethyl-N-nitrosourea (ENU) on spermatogonia of mice by using visible loci and a hemoglobin beta-chain (Hbb) locus. Male wild-type (C3Hf/He) mice were injected intraperitoneally with ENU. 8 weeks after injection, these males were mated with tester strain...

Topics

Animals
Crosses, Genetic
Electrophoresis, Cellulose Acetate
Ethylnitrosourea
Female
Hemoglobins
Macromolecular Substances
Male
Mice
Mice, Inbred Strains
Mutation
Nitrosourea Compounds

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