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Article

Delayed Hepatocellular Mitotic Progression and Impaired Liver Regeneration in Early Growth Response-1-deficient Mice

21 Jul 2004

Abstract excerpt

The early growth response-1 transcription factor (Egr-1) is induced as part of the immediate-early gene expression response during early liver regeneration. In the studies reported here the functional significance of EGR-1 expression during liver regeneration was examined by characterizing the hepatic regenerative response to partial hepatectomy in Egr-1 null mice. The results of these studies showed that liver...

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Identifiers

PMID: 15265859
DOI: 10.1074/jbc.m407969200

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Source receipt: pubmed, retrieved 7 Sept 2026.

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