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Article

Analysis of K-ras, p53 and c-raf-1 mutations in beryllium-induced rat lung tumors.

Carcinogenesis - 1 Feb 1994

Nickell-Brady C, Hahn F F, Finch G L, Belinsky S A

Abstract excerpt

Beryllium (Be) metal and several of its analogues have been shown to be carcinogenic in rats. In addition, workers employed at Be processing plants have been shown to have a slight excess of lung cancer. In this study, a single inhalation exposure to Be metal produced a 64% incidence of lung tumors in the F344/N rat. The most frequent tumor type observed was adenocarcinoma. These Be metal-induced lung carcinomas...

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Identifiers

PMID: 7545909
DOI: 10.1093/carcin/15.2.257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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