Article
Carcinogenic potential and genomic instability of beryllium sulphate in BALB/c-3T3 cells.
Molecular and cellular biochemistry - 1 Jun 2001
Keshava N, Zhou G, Spruill M, Ensell M, Ong T M
Abstract excerpt
Occupational exposure to beryllium (Be) and Be compounds occurs in a wide range of industrial processes. A large number of workers are potentially exposed to this metal during manufacturing and processing, so there is a concern regarding the potential carcinogenic hazard of Be. Studies were performed to determine the carcinogenic potential of beryllium sulfate (BeSO4) in cultured mammalian cells. BALB/c-3T3 cells...
Topics
- 3T3 Cells
- Animals
- Beryllium
- Carcinogenicity Tests
- Cell Division
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Fibrosarcoma
- Gene Amplification
- Genes, jun
- Genes, ras