Article
Contribution of B cell subsets to delayed development of MAIDS in xid mice.
Cellular immunology - 1 Oct 1995
Tang Y, Kim W K, Holmes K L, Hügin A W, Kenny J J, Chattopadhyay S K, Hartley J W, Morse H C
Abstract excerpt
C57BL/6 (B6) mice develop a syndrome of progressive lymphoproliferation and immunodeficiency, murine AIDS (MAIDS), when infected with an etiologic replication-defective virus termed BM5def. Induction of MAIDS requires the presence of CD4+ T cells and B cells. B6 mice with altered conventional B c...
Topics
- Agammaglobulinaemia Tyrosine Kinase
- Animals
- Antigens, CD
- B-Lymphocyte Subsets
- Bone Marrow Transplantation
- CD5 Antigens
- Flow Cytometry
- Immunologic Deficiency Syndromes
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mice, Transgenic
- Murine Acquired Immunodeficiency Syndrome
- Mutation
- Protein-Tyrosine Kinases
- X Chromosome