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Article

Unexpected effects of the severe combined immunodeficiency mutation on murine lymphomagenesis.

The Journal of experimental medicine - 1 Aug 1992

Lieberman M, Hansteen G A, Waller E K, Weissman I L, Sen-Majumdar A

Abstract excerpt

Strain C.B17 scid/scid (SCID) mice, which lack functional T and B lymphocytes, show heightened susceptibility to the induction of thymic lymphomas by x-irradiation. Susceptibility is highest in thymus-chimeric SCID-BL mice (thymectomized SCID mice bearing a C57BL thymus graft). All SCID-BL lymphomas originate in the cells of the thymic graft (C57BL type) and lack murine leukemia virus expression. Both SCID and...

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Source

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Identifiers

PMID: 1500852
DOI: 10.1084/jem.176.2.399
PMCID: PMC2119309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Unexpected effects of the severe combined immunodeficiency mutation on murine lymphomagenesis.PMID 1500852Read ↗

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