Article
Accelerated progression of a murine retrovirus-induced immunodeficiency syndrome in Fas mutant C57BL/6 lpr/lpr mice.
Microbiology and immunology - 1 Jan 1997
Hiromatsu K, Usami J, Aoki Y, Makino M, Yoshikai Y
Abstract excerpt
We reported previously that CD4+ T cells and B cells in mice with retrovirus-induced murine acquired immunodeficiency syndrome (MAIDS) caused by LP-BM5 murine leukemia virus (MuLV) mixtures increased the expression of Fas antigen (Fas) during progression of the disease. However, the contribution...
Topics
- Animals
- Apoptosis
- Defective Viruses
- Disease Progression
- Leukemia Virus, Murine
- Mice
- Mice, Inbred C57BL
- Mice, Inbred MRL lpr
- Mice, Mutant Strains
- Murine Acquired Immunodeficiency Syndrome
- Phenotype
- RNA, Viral
