Article
Accelerated progression of a murine retrovirus-induced immunodeficiency syndrome in Fas mutant C57BL/6 lpr/lpr mice.
Microbiology and immunology - 1 Jan 1997
Hiromatsu K, Usami J, Aoki Y, Makino M, Yoshikai Y
Abstract excerpt
We reported previously that CD4+ T cells and B cells in mice with retrovirus-induced murine acquired immunodeficiency syndrome (MAIDS) caused by LP-BM5 murine leukemia virus (MuLV) mixtures increased the expression of Fas antigen (Fas) during progression of the disease. However, the contribution of the Fas/Fas ligand (Fas L) system to the pathogenesis of MAIDS remained unknown. Here, we examined the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
