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Article

The Xid defect determines an improved clinical course of murine leishmaniasis in susceptible mice

1 Jan 1994

Abstract excerpt

The course of Leishmania major infection in B cell-defective BALB.Xid mice was investigated. Infected BALB.Xid mice showed a significantly slower lesion development compared with BALB/c controls accompanied by a 10- to 30-fold lower parasite burden in lymphatic organs. The B cell immune response, as quantified by anti-leishmanial antibody production and B cell numbers in lymphatic organs, remained significantly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 7981141
DOI: 10.1093/intimm/6.8.1117

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Source receipt: pubmed, retrieved 7 Sept 2026.

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