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Article

Delayed progression of a murine retrovirus-induced acquired immunodeficiency syndrome in X-linked immunodeficient mice.

The Journal of experimental medicine - 1 Mar 1993

Hitoshi Y, Okada Y, Sonoda E, Tominaga A, Makino M, Suzuki K, Kinoshita J, Komuro K, Mizuochi T, Takatsu K

Abstract excerpt

The murine acquired immunodeficiency syndrome (MAIDS) caused by defective LP-BM5 murine leukemia virus (MuLV) is a disease that shows severe immunodeficiency with abnormal lymphoproliferation, and hypergammaglobulinemia in susceptible C57BL/6 (B6) mice. To examine the cellular mechanisms of development of MAIDS, we injected LP-BM5 MuLV intraperitoneally into B6 mice bearing the X chromosome-linked...

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Identifiers

PMID: 8382252
DOI: 10.1084/jem.177.3.621
PMCID: PMC2190950

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