Article
The effect of carrier and carrier priming on the kinetics and pattern of somatic mutation in the V chi Ox1 gene.
European journal of immunology - 1 Aug 1995
Källberg E, Gray D, Leanderson T
Abstract excerpt
Priming mice with a chicken gamma globulin (CGG) carrier protein significantly accelerated the onset of somatic mutation in the V chi Ox1 gene when the mice were subsequently immunized with 2-phenyl-5-oxazolone (phOx) coupled to CGG. The first mutations were already detected 7 days after immuniza...
Topics
- Animals
- Base Sequence
- Chickens
- Immunoglobulin Variable Region
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Ovalbumin
- Oxazolone
- Serum Albumin
- gamma-Globulins