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Article

Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1995

Frenette P S, Johnson R C, Hynes R O, Wagner D D

Abstract excerpt

P-selectin, found in storage granules of platelets and endothelial cells, can be rapidly expressed upon stimulation. Mice lacking this membrane receptor exhibit a severe impairment of leukocyte rolling. We observed that, in addition to leukocytes, platelets were rolling in mesenteric venules of wild-type mice. To investigate the role of P-selectin in this process, resting or activated platelets from wild-type or...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 7543682
DOI: 10.1073/pnas.92.16.7450
PMCID: PMC41357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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