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Article

Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction.

Blood - 3 Sept 2015

Armstrong Paul C J, Kirkby Nicholas S, Chan Melissa V, Finsterbusch Michaela, Hogg Nancy, Nourshargh Sussan, Warner Timothy D

Abstract excerpt

Testing of platelet function is central to the cardiovascular phenotyping of genetically modified mice. Traditional platelet function tests have been developed primarily for testing human samples and the volumes required make them highly unsuitable for the testing of mouse platelets. This limits research in this area. To address this problem, we have developed a miniaturized whole blood aggregometry assay, based...

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Identifiers

PMID: 26215112
DOI: 10.1182/blood-2015-01-621656
PMCID: PMC4559940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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