Article
Differential expression of the H-ras mutated and normal alleles in rabbit DMBA-induced keratoacanthomas.
International journal of cancer - 29 May 1995
Matesanz F, Oliva M R, Villamarin A, Kamino H, Pellicer A
Abstract excerpt
Keratoacanthomas (KAs) are benign and self-regressing tumors in which a high incidence of the mutated H-ras oncogene has been observed both in humans and in experimental models. To determine the level of expression of the mutated H-ras allele with respect to its normal counterpart in 7,12-dimethy...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Alleles
- Animals
- Base Sequence
- Gene Expression
- Genes, ras
- Keratoacanthoma
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- RNA-Directed DNA Polymerase
- Rabbits
- Skin Neoplasms
