Article
Differential expression of the H-ras mutated and normal alleles in rabbit DMBA-induced keratoacanthomas.
International journal of cancer - 29 May 1995
Matesanz F, Oliva M R, Villamarin A, Kamino H, Pellicer A
Abstract excerpt
Keratoacanthomas (KAs) are benign and self-regressing tumors in which a high incidence of the mutated H-ras oncogene has been observed both in humans and in experimental models. To determine the level of expression of the mutated H-ras allele with respect to its normal counterpart in 7,12-dimethylbenz(a)anthracene (DMBA)-induced KAs in rabbit skin, we have utilized a quantitative technique based on reverse...
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