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Article

Analysis of gene expression profiles of forestomach tumors in rasH2 mice initiated with N-ethyl-N-nitrosourea.

Archives of toxicology - 1 Dec 2004

Okamura Miwa, Sumida Kayo, Muto Tomoko, Kashida Yoko, Machida Noboru, Watanabe Tomoyuki, Mitsumori Kunitoshi

Abstract excerpt

To clarify the mechanisms underlying enhancement of carcinogenesis in transgenic mice carrying a human prototype c-Ha- ras gene (rasH2 mouse), animals received a single intraperitoneal injection of 120 mg/kg N-ethyl-N-nitrosourea (ENU) and at 20 weeks thereafter expression profiles in three induced forestomach squamous cell carcinomas were assessed using high-density oligonucleotide microarrays. In addition, the...

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Source

Identifiers

PMID: 15249993
DOI: 10.1007/s00204-004-0589-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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