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Article

Oncogene involvement in tumor regression: H-ras activation in the rabbit keratoacanthoma model.

Oncogene - 1 Apr 1991

Corominas M, Leon J, Kamino H, Cruz-Alvarez M, Novick S C, Pellicer A

Abstract excerpt

Activated H-ras genes are present in a number of skin tumors induced in animals by carcinogen treatment. The involvement of the ras oncogenes in tumorigenesis was investigated in keratoacanthomas, benign and self-regressing tumors, as well as malignant squamous cell carcinomas. Both tumors were induced in rabbit ears by repeated applications of 7,12 dimethylbenz(a)anthracene (DMBA). The rabbit H-ras gene was...

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PMID: 1840681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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