Article
DNA-repeat instability is associated with colorectal cancers presenting minimal chromosome rearrangements.
Genes, chromosomes & cancer - 1 Apr 1995
Remvikos Y, Vogt N, Muleris M, Salmon R J, Malfoy B, Dutrillaux B
Abstract excerpt
The DNA-repeat [(CA)n] instability of colorectal cancer cells was studied relative to our previously defined classification based on chromosome alterations. Of the 23 tumors analyzed, 13 belonged to the "monosomic" type (MT) characterized by simultaneous loss of chromosome 18 and chromosome arm 17p, and many structural rearrangements, 7 to the "trisomic" type (TT) with many chromosome gains but few...
Topics
- Adult
- Aged
- Aged, 80 and over
- Chromosome Aberrations
- Chromosomes, Human, Pair 2
- Chromosomes, Human, Pair 3
- Colonic Neoplasms
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA, Neoplasm