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Article

Impact of chromosomal instability on colorectal cancer progression and outcome

22 Feb 2014

Abstract excerpt

BACKGROUND: It remains presently unclear whether disease progression in colorectal carcinoma (CRC), from early, to invasive and metastatic forms, is associated to a gradual increase in genetic instability and to a scheme of sequentially occurring Copy Number Alterations (CNAs). METHODS: In this work we set to determine the existence of such links between CRC progression and genetic instability and searched for...

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PMID: 24559140
DOI: 10.1186/1471-2407-14-121

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