Alterations of (CA)n DNA repeats and tumor suppressor genes in human gastric cancer.

Article

Alterations of (CA)n DNA repeats and tumor suppressor genes in human gastric cancer.

Cancer research - 1 Jan 1994

Mironov N M, Aguelon M A, Potapova G I, Omori Y, Gorbunov O V, Klimenkov A A, Yamasaki H

Abstract excerpt

We have examined whether alterations of simple (CA)n DNA repeats, as observed in human colon cancers, occur during human gastric carcinogenesis and whether such alterations reflect genomic instability that could lead to other genetic changes. A total of 22 gastric cancer samples were analyzed: 15...

Topics

Adenocarcinoma
Adult
Aged
Base Sequence
DNA, Neoplasm
Female
Gene Deletion
Genes, p53
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Stomach Neoplasms

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