Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas.

doi:10.1002/gcc.22243

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Article

Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas.

Genes, chromosomes & cancer - 1 May 2015

Zarzour Peter, Boelen Lies, Luciani Fabio, Beck Dominik, Sakthianandeswaren Anuratha, Mouradov Dmitri, Sieber Oliver M, Hawkins Nicholas J, Hesson Luke B, Ward Robyn L, Wong Jason W H

Abstract excerpt

The progression of benign colorectal adenomas into cancer is associated with the accumulation of chromosomal aberrations. Even though patterns and frequencies of chromosomal aberrations have been well established in colorectal carcinomas, corresponding patterns of aberrations in adenomas are less well documented. The aim of this study was to profile chromosomal aberrations across colorectal adenomas and...

Topics

Adenoma
Aged
Aged, 80 and over
Carcinoma
Chromosome Aberrations
Colorectal Neoplasms
Disease Progression
Female
Gene Expression Profiling
Humans
Male
Middle Aged
Neoplasm Staging

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligonucleotide Array Sequence Analysis

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 25726927
DOI: 10.1002/gcc.22243

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