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Article

The myelin basic protein gene is not a major susceptibility locus for multiple sclerosis in Italian patients.

Journal of neurology - 1 Oct 1994

Eoli M, Pandolfo M, Milanese C, Gasparini P, Salmaggi A, Zeviani M

Abstract excerpt

To verify whether multiallelic polymorphism adjacent to the gene encoding for myelin basic protein is associated with or linked to multiple sclerosis in Italians, we studied 54 sporadic patients, 55 control subjects and 18 families with two or more affected individuals. Allelic typing was carried out by analysis of fragment length polymorphisms after DNA amplification by the polymerase chain reaction. The...

Topics

Adult
Base Sequence
DNA
DNA Primers
Female
Genetic Linkage
Genetic Predisposition to Disease
Humans
Italy
Male
Middle Aged
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multiple Sclerosis

Myelin Basic Protein

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 7530769
DOI: 10.1007/BF00920626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7530769-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The myelin basic protein gene is not a major susceptibility locus for multiple sclerosis in Italian patients.PMID 7530769Read ↗

Genetic susceptibility in familial multiple sclerosis not linked to the myelin basic protein gene.Semantic proximity Read ↗

Evidence of linkage between susceptibility to multiple sclerosis and HLA-class II loci in Italian multiplex families.Semantic proximity Read ↗

Lack of replication of KIF1B gene in an Italian primary progressive multiple sclerosis cohort.Semantic proximity Read ↗

No linkage or association between multiple sclerosis and the myelin basic protein gene in affected sibling pairs.Semantic proximity Read ↗

Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene.Semantic proximity Read ↗

The myelin basic protein gene in multiple sclerosis: identification of discrete alleles of a 1.3 kb tetranucleotide repeat sequence.Semantic proximity Read ↗

Linkage analysis of candidate myelin genes in familial multiple sclerosis.Semantic proximity Read ↗

Myelin basic protein gene is associated with MS in DR4- and DR5-positive Italians and Russians.Semantic proximity Read ↗

Vitamin D-binding protein gene polymorphisms are not associated with MS risk in an Italian cohort.Semantic proximity Read ↗

Lack of evidence for a role of the myelin basic protein gene in multiple sclerosis susceptibility in Sardinian patients.Semantic proximity Read ↗

A polymorphism in the repetitive (TGGA)n sequence 5' to the human myelin basic protein gene in Italian multiple sclerosis patients.Semantic proximity Read ↗

Lack of relationship between the P413L chromogranin B variant and a SALS Italian cohort.Semantic proximity Read ↗

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