The myelin basic protein gene in multiple sclerosis: identification of discrete alleles of a 1.3 kb tetranucleotide repeat sequence.

doi:10.1111/j.1600-0404.1998.tb00608.x

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Article

The myelin basic protein gene in multiple sclerosis: identification of discrete alleles of a 1.3 kb tetranucleotide repeat sequence.

Acta neurologica Scandinavica - 1 Jan 1998

He B, Yang B, Lundahl J, Fredrikson S, Hillert J

Abstract excerpt

Myelin basic protein (MBP) is a potential autoantigen in multiple sclerosis (MS) and its gene therefore is an attractive candidate to confer genetic susceptibility to this disease. Linkage and association with certain alleles of a 1.2 kb tetranucleotide repeat region 5' to the MBP gene with MS have been reported in Finnish patients, and an association has been reported from Denmark. However, these findings have...

Topics

Alleles
Genetic Linkage
Genotype
Humans
Multiple Sclerosis
Myelin Basic Protein
Polymorphism, Genetic
Repetitive Sequences, Nucleic Acid
Risk Factors

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Open in PubMed

Identifiers

PMID: 9482678
DOI: 10.1111/j.1600-0404.1998.tb00608.x

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