Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene.

doi:10.1016/0140-6736(92)93007-a

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Article

Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene.

Lancet (London, England) - 24 Oct 1992

Tienari P J, Wikström J, Sajantila A, Palo J, Peltonen L

Abstract excerpt

Genetic factors have been implicated in the aetiology of multiple sclerosis (MS), but the genes conferring susceptibility to MS have not been identified. We carried out genetic linkage and association analyses by studying polymorphism of the myelin basic protein (MBP) gene on chromosome 18, a can...

Topics

Adult
Aged
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 18
Confounding Factors, Epidemiologic
DNA
Female
Finland
Gene Frequency
Genes, Dominant
Genetic Linkage
Genetic Predisposition to Disease
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Molecular Sequence Data

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PMID: 1383661
DOI: 10.1016/0140-6736(92)93007-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1383661-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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