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Article

Genetic susceptibility in familial multiple sclerosis not linked to the myelin basic protein gene.

Lancet (London, England) - 8 May 1993

Rose J, Gerken S, Lynch S, Pisani P, Varvil T, Otterud B, Leppert M

Abstract excerpt

The myelin basic protein (MBP) gene is a candidate locus for disease susceptibility in familial multiple sclerosis. Amplification of a polymorphic tetranucleotide repeat region immediately 5' to MBP exon 1 demonstrated the presence of eight different alleles among members of 14 multiplex multiple sclerosis families (36 affected individuals). Linkage analysis was performed with autosomal dominant and autosomal...

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Source

Identifiers

PMID: 7683738
DOI: 10.1016/0140-6736(93)91003-5

Genes

MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic susceptibility in familial multiple sclerosis not linked to the myelin basic protein gene.PMID 7683738Read ↗

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