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Article

Lack of evidence for a role of the myelin basic protein gene in multiple sclerosis susceptibility in Sardinian patients.

Journal of neurology - 1 Nov 2002

Cocco Eleonora, Mancosu Cristina, Fadda Elisabetta, Murru Maria Rita, Costa Gianna, Murru Raffaele, Marrosu Maria Giovanna

Abstract excerpt

A link between myelin basic protein (MBP) polymorphism and multiple sclerosis (MS) has been reported in some populations but not in others. We analysed two polymorphisms in the 5' flanking region of the MBP exon 1 gene in MS patients from the founder population of Sardinia. Using the transmission disequilibrium test (TDT), MBP polymorphisms were analysed in 363 singleton MS families. No distortion in transmission...

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Source

Identifiers

PMID: 12420096
DOI: 10.1007/s00415-002-0888-9

Genes

MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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