Article
Myelin basic protein gene is associated with MS in DR4- and DR5-positive Italians and Russians.
Neurology - 26 Aug 2003
Guerini F R, Ferrante P, Losciale L, Caputo D, Lombardi M L, Pirozzi G, Luongo V, Sudomoina M A, Andreewski T V, Alekseenkov A D, Boiko A N, Gusev E I, Favorova O O
Abstract excerpt
BACKGROUND: The myelin basic protein (MBP) gene may confer genetic susceptibility to multiple sclerosis (MS). The association of MS with alleles of the (TGGA)n variable number tandem repeat (VNTR) 5' to the MBP gene is the subject of conflicting reports. OBJECTIVE: To study possible MS association with VNTR alleles of MBP gene in ethnic Italians and ethnic Russians. METHODS: Two hundred sixty-nine unrelated...
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