Article
Lack of replication of KIF1B gene in an Italian primary progressive multiple sclerosis cohort.
European journal of neurology - 1 May 2010
Martinelli-Boneschi F, Esposito F, Scalabrini D, Fenoglio C, Rodegher M E, Brambilla P, Colombo B, Ghezzi A, Capra R, Collimedaglia L, Coniglio G, De Riz M, Serpente M, Cantoni C, Scarpini E, Martinelli V, Galimberti D, Comi G
Abstract excerpt
BACKGROUND: KIF1B gene represents the first non-inflammatory gene with a putative role on axonal loss and neurodegeneration found to be associated with multiple sclerosis (MS). The objective of this study is to test the association of the rs10492972 C allelic variant of KIF1B gene in a large Italian cohort of patients with primary progressive and progressive relapsing MS (PPMS and PRMS), which represents a...
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