Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A polymorphism in the repetitive (TGGA)n sequence 5' to the human myelin basic protein gene in Italian multiple sclerosis patients.

Journal of neurovirology - 1 May 2000

Guerini F R, Losciale L, Mediati M, Speciale L, Mancuso R, Saresella M, Calvo M G, Caputo D, Ferrante P

Abstract excerpt

Human myelin basic protein (hMBP) gene is one of the candidate genes in the complex mosaic of multiple sclerosis (MS) susceptibility. In this study we verified the distribution of the polymorphism of the region 5' flanking the first exon of the hMBP gene, in 97 relapsing remitting, 74 primary progressive Italian MS patients, and in 236 healthy controls, using polymerase chain reaction (PCR) and gel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Multiple Sclerosis, Chronic Progressive

Share to Multiple Sclerosis, Relapsing-Remitting

Share to Myelin Basic Protein

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 10871781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism in the repetitive (TGGA)n sequence 5' to the human myelin basic protein gene in Italian multiple sclerosis patients.PMID 10871781Read ↗

PCR typing of two short tandem repeat (STR) structures upstreams of the human myelin basic protein (MBP) gene; the genetic susceptibility in multiple sclerosis and monosymptomatic idiopathic optic neuritis in Danes.Semantic proximity Read ↗

Characteristic imprint of single nucleotide polymorphisms in multiple sclerosis.Semantic proximity Read ↗

Four frequently observed polymorphisms in the 3'-UTR of human peripheral myelin protein 22 (PMP22): identification of different haplotypes.Semantic proximity Read ↗

Myelin basic protein gene is associated with MS in DR4- and DR5-positive Italians and Russians.Semantic proximity Read ↗

Identification of single nucleotide variations in the coding and regulatory regions of the myelin-associated glycoprotein gene and study of their association with multiple sclerosis.Semantic proximity Read ↗

Golli-MBP gene in multiple sclerosis susceptibility.Semantic proximity Read ↗

A genetic study of the FMR1 gene in a Sardinian multiple sclerosis population.Semantic proximity Read ↗

DNA sequence and polymorphism analysis of a region of the T-cell receptor beta locus thought to contain a susceptibility gene for multiple sclerosis.Semantic proximity Read ↗

The variant methylenetetrahydrofolate reductase c.1298A>C (p.E429A) is associated with multiple sclerosis in a German case-control study.Semantic proximity Read ↗

The evaluation of VEGF and HIF-1α gene polymorphisms and multiple sclerosis susceptibility.Semantic proximity Read ↗

Tumour necrosis factor alpha gene (TNF-alpha) -376 polymorphism in Hungarian patients with primary progressive multiple sclerosis.Semantic proximity Read ↗

Linkage disequilibrium between the MBP tetranucleotide repeat and multiple sclerosis is restricted to a geographically defined subpopulation in Finland.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.