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Article

Novel SOS phenotypes caused by second-site mutations in the recA430 gene of Escherichia coli.

Biochimie - 1 Apr 1991

Sweasy J B, Witkin E M

Abstract excerpt

E coli recA430 mutants are recombination-proficient, extremely UV sensitive, UV nonmutable and partially deficient in RecA-mediated proteolysis and in RecA-dependent 'induced replisome reactivation' (IRR), the ability to recover DNA replication activity after UV irradiation. To determine how this pleiotropic phenotype can be altered by mutation, we isolated 10 independent derivatives of a recA430 strain,...

Topics

Bacterial Proteins
DNA Replication
DNA, Bacterial
Escherichia coli
Genes, Bacterial
Mutagenesis
Phenotype
Rec A Recombinases
Recombination, Genetic
Repressor Proteins
SOS Response, Genetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serine Endopeptidases

Ultraviolet Rays

Source

Identifiers

PMID: 1911944
DOI: 10.1016/0300-9084(91)90111-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1911944-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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