Article
Analysis of HLA-DMB mutants and -DMB genomic structure.
Immunogenetics - 1 Jan 1995
Shaman J, von Scheven E, Morris P, Chang M D, Mellins E
Abstract excerpt
The HLA-DM locus encodes class II-like A and B chains and apparently regulates the antigen presentation function of conventional major histocompatibility complex (MHC) class II molecules. Here we describe the HLA-DMB mutations in three presentation defective B lymphoblastoid cells lines (B-LCL),...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA, Complementary
- Exons
- Genes, MHC Class II
- HLA-D Antigens
- Histocompatibility Antigens Class II
- Humans
- Introns
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- RNA Splicing
- RNA, Messenger
- RNA-Directed DNA Polymerase
- Sequence Analysis, DNA
- Transcription, Genetic