Article
The DMB promoter: delineation, in vivo footprint, trans-activation, and trans-dominant suppression.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1997
Ting J P, Wright K L, Chin K C, Brickey W J, Li G
Abstract excerpt
The HLA-DM loci encode the heterodimeric unconventional class II MHC molecules that are coexpressed with conventional class II MHC molecules. DM molecules are essential for the proper formation and function of conventional class II MHC molecules. This report characterizes the DMB promoter both by in vivo footprint and by in vitro functional analysis and reveals a promoter structure similar to that of conventional...
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