Article
The DMB promoter: delineation, in vivo footprint, trans-activation, and trans-dominant suppression.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1997
Ting J P, Wright K L, Chin K C, Brickey W J, Li G
Abstract excerpt
The HLA-DM loci encode the heterodimeric unconventional class II MHC molecules that are coexpressed with conventional class II MHC molecules. DM molecules are essential for the proper formation and function of conventional class II MHC molecules. This report characterizes the DMB promoter both by...
Topics
- Base Sequence
- Cell Line
- DNA Footprinting
- DNA-Binding Proteins
- Genes, MHC Class II
- HLA-D Antigens
- Histocompatibility Antigens Class II
- Humans
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Regulatory Factor X Transcription Factors
- Trans-Activators
- Transcription Factors
- Transfection