Article
A minimum of four human class II alpha-chain genes are encoded in the HLA region of chromosome 6.
Nature - 1 Jan 2000
Auffray C, Kuo J, DeMars R, Strominger J L
Abstract excerpt
The major histocompatibility complex (MHC) in man, also called the HLA region, is located on the short arm of chromosome 6 and encodes antigens involved in immunological processes. The class II HLA antigens consist of two noncovalently associated polypeptide chains, one of molecular weight 34,000 (alpha) and the other of molecular weight 29,000 (beta). The extensive polymorphism of the beta chain(s) has allowed...
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