A minimum of four human class II alpha-chain genes are encoded in the HLA region of chromosome 6.

doi:10.1038/304174a0

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Article

A minimum of four human class II alpha-chain genes are encoded in the HLA region of chromosome 6.

Nature - 1 Jan 2000

Auffray C, Kuo J, DeMars R, Strominger J L

Abstract excerpt

The major histocompatibility complex (MHC) in man, also called the HLA region, is located on the short arm of chromosome 6 and encodes antigens involved in immunological processes. The class II HLA antigens consist of two noncovalently associated polypeptide chains, one of molecular weight 34,000...

Topics

Base Sequence
Chromosomes, Human, 6-12 and X
Cloning, Molecular
DNA
DNA Restriction Enzymes
Genes
HLA Antigens
Humans
Major Histocompatibility Complex
Mutation
Nucleic Acid Hybridization
Polymorphism, Genetic

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