Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance.

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Article

Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance.

Hepatology (Baltimore, Md.) - 1 Jan 1995

Lok A S, Akarca U S, Greene S

Abstract excerpt

We previously reported two mutually exclusive mutations in the precore region of hepatitis B virus: M1 (T-1856, proline-serine substitution at codon 15) and M2 (A-1896, stop codon at codon 28). This study was conducted to determine if the presence of precore mutants affect spontaneous or interfer...

Topics

Base Sequence
Clinical Trials as Topic
Hepatitis B
Hepatitis B Core Antigens
Hepatitis B e Antigens
Humans
Interferons
Longitudinal Studies
Molecular Probes
Molecular Sequence Data
Mutation
Predictive Value of Tests

Source

Open in PubMed

Identifiers

PMID: 7528709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7528709-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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