Article
Hepatitis B virus infection: precore mutants and its relation to viral genotypes and core mutations.
Hepatology (Baltimore, Md.) - 1 Dec 1995
Rodriguez-Frias F, Buti M, Jardi R, Cotrina M, Viladomiu L, Esteban R, Guardia J
Abstract excerpt
The precore-core gene of hepatitis B virus (HBV) was directly sequenced from serum samples of 42 patients with chronic B hepatitis (19 hepatitis B e antigen [HBeAg]+ and 23 anti-HBE+). Viral genotypes were determined by comparison with 11 reference sequences and by restriction analysis. Genotype...
Topics
- Adolescent
- Adult
- Base Composition
- Base Sequence
- DNA, Viral
- Female
- Genotype
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Core Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation