Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Response to interferon-alpha in chronic hepatitis B with and without precore mutant strain detected by mutation site-specific assay.

Journal of clinical gastroenterology - 1 Jan 2000

Seo Yasushi, Yoon Seitetsu, Hamano Kenichi, Nakaji Miyuki, Yano Yoshihiko, Katayama Megumi, Ninomiya Toshiaki, Hayashi Yoshitake, Kasuga Masato

Abstract excerpt

GOALS: We investigated whether the presence of precore mutant (stop codon mutation at codon 28) affects the response to interferon-alpha in patients with chronic hepatitis B. BACKGROUND: Mutations of hepatitis B virus (HBV) may influence the response to treatment. The association of precore mutant with the response to interferon is controversial. STUDY: Thirty-one Japanese patients with hepatitis B e...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Interferon-alpha

Share to Mutation

Share to Treatment Outcome

Source

Identifiers

PMID: 15100528
DOI: 10.1097/00004836-200405000-00013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Response to interferon-alpha in chronic hepatitis B with and without precore mutant strain detected by mutation site-specific assay.PMID 15100528Read ↗

Precore stop mutant in HBeAg-positive patients with chronic hepatitis B: clinical characteristics and correlation with the course of HBeAg-to-anti-HBe seroconversion.Semantic proximity Read ↗

Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance.Semantic proximity Read ↗

Genetic heterogeneity in the precore region of hepatitis B virus in hepatitis B e antigen-negative chronic hepatitis B patients: spontaneous seroconversion and interferon-induced seroconversion.Semantic proximity Read ↗

Hepatitis B virus precore mutants in HBeAg carriers with chronic hepatitis treated with interferon.Semantic proximity Read ↗

Hepatitis B virus infection: precore mutants and its relation to viral genotypes and core mutations.Semantic proximity Read ↗

The precore mutation is associated with severity of liver damage in Brazilian patients with chronic hepatitis B.Semantic proximity Read ↗

Point mutation in precore region of hepatitis B virus: sequential changes from 'wild' to 'mutant'.Semantic proximity Read ↗

Association between frequency of amino acid changes in core region of hepatitis B virus (HBV) and the presence of precore mutation in Japanese HBV carriers.Semantic proximity Read ↗

Universal emergence of precore mutant hepatitis B virus along with seroconversion to anti-HBe irrespective of subsequent activity of chronic hepatitis B.Semantic proximity Read ↗

Interferon therapy for fulminant hepatitis associated with precore region mutation in hepatitis B virus carrier.Semantic proximity Read ↗

Hepatitis B virus precore mutants are identical in carriers from various ethnic origins and are associated with a range of liver disease severity.Semantic proximity Read ↗

Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.