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Article

Precore sequence variation in Chinese isolates of hepatitis B virus.

The Journal of infectious diseases - 1 Jan 1992

Carman W F, Ferrao M, Lok A S, Ma O C, Lai C L, Thomas H C

Abstract excerpt

Direct sequencing of polymerase chain reaction-amplified serum hepatitis B virus (HBV) DNA was used to characterize the precore region of HBV from Chinese patients with chronic hepatitis. Two types of mutually exclusive variants were found in hepatitis B e antigen (HBeAg)-negative patients. The first (M1) contains a substitution from proline to serine at codon 15. A second group were infected with a previously...

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Identifiers

PMID: 1727881
DOI: 10.1093/infdis/165.1.127

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