Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members.

Article

Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members.

Hepatology (Baltimore, Md.) - 1 Jun 1994

Akarca U S, Greene S, Lok A S

Abstract excerpt

Precore hepatitis B virus mutants have been detected mainly in HBeAg-negative patients with active liver disease. We previously reported two novel mutations: M1 (C-to-T change at nucleotide 1856 [proser at codon 15]) and M3 (G-to-A change at nucleotide 1898 [gly-ser at codon 29]) in addition to t...

Topics

Adolescent
Adult
Base Sequence
Carrier State
Child
Child, Preschool
DNA Primers
DNA, Viral
Family
Female
Follow-Up Studies
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Hepatitis B virus
Humans
Male
Middle Aged

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