Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan.

doi:10.1016/0042-6822(91)90799-h

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Article

Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan.

Virology - 1 Nov 1991

Hasegawa K, Huang J K, Wands J R, Obata H, Liang T J

Abstract excerpt

We studied the precore DNA sequences of hepatitis B viral genomes in five patients with fulminant hepatitis B and in five with acute self-limited hepatitis B from Japan. Using the polymerase chain reaction, three to four independent HBV DNA clones from each patient were obtained and analyzed. We...

Topics

Adult
Base Sequence
Cloning, Molecular
Female
Genome, Viral
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Hepatitis B virus
Humans
Immunoglobulin M
Male
Middle Aged
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides
Polymerase Chain Reaction
Restriction Mapping

Source

Open in PubMed

Identifiers

PMID: 1926786
DOI: 10.1016/0042-6822(91)90799-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1926786-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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