Article
Several HLA alleles share overlapping peptide specificities.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 1995
Sidney J, del Guercio M F, Southwood S, Engelhard V H, Appella E, Rammensee H G, Falk K, Rötzschke O, Takiguchi M, Kubo R T
Abstract excerpt
Herein we describe the establishment of assays to measure peptide binding to purified HLA-B*0701, -B*0801, -B*2705, -B*3501-03, -B*5401, -Cw*0401, -Cw*0602, and -Cw*0702 molecules. The binding of known peptide epitopes or naturally processed peptides correlates well with HLA restriction or origin, underscoring the immunologic relevance of these assays. Analysis of the sequences of various HLA class I alleles...
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